A research study titled, “Biosimulation Market by Product, Application, and End User - Global Industry Analysis and Forecast to 2025” published by Crystal Market Research, states that the biosimulation market is projected to be around $4 billion by 2025.
A typical
drug discovery and development cycle, which encompasses the time taken for
discovery of a new drug and its delivery to the market, may easily take up to
10 to 15 years. The process of drug discovery which starts with discovering a
new drug molecule to registering the drug for marketing and commercialization
is a very lengthy and complex process. Heavy capital investment, considerable
amount of time and series of clinical trials are required before a drug is
registered for human use. FDA launched the Critical Path Initiative (CPI), in
2004, to promote innovation in scientific processes by which medical products
are developed, examined and manufactured.
Biosimulation
is one such promising notion to drug discovery and development. It has been
developed in order to avoid the hurdles in discovery and development of a new
drug by traditional processes. It promises tremendous benefits saving both
money and time and improves the predictability in early stage of the drug
development. In biosimulation, the relationships between different biological
elements are represented using differential equations utilizing simulation
techniques to predict the behavior of the biological system and status of
biological elements over time.
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Market by Product, Application, and End User - Global Industry Analysis and
Forecast to 2025” at:http://www.crystalmarketresearch.com/report/biosimulation-market
Rise in cases
of chronic diseases such as diabetes, high drug resistance exhibited by certain
disease related pathogens, and rapidly aging population worldwide are some of
the factors encouraging biosimulation market. Moreover, high drug failure rate
and availability of advanced modeling and simulation tools will further
contribute to the market growth.
In 2016, the
software segment accounted for over half of the global market,due to the high
accuracy of computer modeling in biosimulation to improve drug molecules. In
terms of applications, the drug discovery marketis expected to show an
impressive growth rate over the forecast period due to the benefits of
biosimulation processesin assisting the researchers in identifying critical
gaps that hamper the drug discovery process.
Pharmaceutical
and biotechnology companiessegment held more than half of the global market in
2016. This large share can be attributed to the rising acceptance of in silico models (biological experiments
performed entirely by means of a computer) for drug discovery and development.
Large numbers of pharmaceutical and biotechnology companies are aggressively
using computer models to create more advanced and effective drug variants. For example,
in January 2017, Certara, the global biosimulation drug development company,
announced the release of version 16 of its Simcyp Population-based Simulator,
which is one of the most sophisticated platforms to determine first in-human
dose selection.
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U.S.
accounted for the major share of the North American market in 2016, due to the
high prevalence of chronic diseases, rapidly growing elderly population, which
is more prone to these diseases and are in need of treatment options such as
drugs, and strategic collaborations among leading players. For instance,
Certara in September 2016 acquired Australia based d3 Medicine to strengthen
their ability to deliver optimized drug development plans to their
clients.Also, there is rise in research activities on biosimulation in the
region which will facilitate the market growth. For instance, in April 2016,
Certara launched an e-learning platform under Certara University to facilitate
education in the field of biosimulation and model based drug development.
Emerging economies in Asia-Pacific biosimulation market will exhibit the
fastest growth in the forecast period due to emphasis on research and
development initiatives and rising focus of international playerson the
emerging markets. For instance, in January 2016, Certara launched a strategic
drug development consulting company in China, named, Certara Strategic
Consulting.
The
competitive market for biosimulation is driven by strategic collaborations and
acquisitions by leading players to strengthen their research and development
capabilities and to expand their existing product portfolio. For instance, in
late December 2015, Certaraacquired XenologiQ, a UK based quantitative systems
pharmacology (QSP) firm, to strengthen its modeling and simulation
capabilities. Some of the leading players in biosimulation market are, Certara
USA, Inc., DassaultSystèmesSA, Accelrys,
Compugen, Rhenovia Pharma, Leadscope Inc., Simulations Plus, Inc. and Evidera,
Inc.
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Key Findings of the Research Study:
·
The biosimulation market will be majorly driven by rise
in chronic disease incidence such as cancer and diabetes, increasing prevalence
of geriatric population, high drug resistance by certain disease related
pathogens and high drug failure rate.
·
The services segment will exhibit favorable growth over
the forecast period as more and more pharmaceutical companies are beginning to
outsource their biosimulation processes in order to reduce costs and focus on
core competencies.
·
North America held a major share of the biosimulation
market in 2016, commanding over more than half of the market. Due to presence
of highly skilled professionals and research infrastructure along with presence
of regulatory authorities ensuring patient safety, this market will show
promising growth over the forecast period.
·
Asia-Pacific market will exhibit the fastest growth rate
during the forecast period due to rapidly improving healthcare infrastructure
and growing Healthcare IT expenditure.
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Biosimulation
market is segmented as follows:
By Product:
·
Services
o
In-house Services
o
Contract/External Services
- Software
o
Toxicity Prediction Software
o
Molecular Modeling and Simulation Software
o
Trial Design Software
o
PK/PD Modeling and Simulation Software
o
PBPK Modeling and Simulation Software
o
Other Software (QSP, Visualizing and Analytical
Software)
By Application:
·
Drug Discovery
o
Target Identification and Optimization
o
Lead Identification and Optimization
·
Drug Development
o
In Patient Validation
o
Preclinical Testing and Clinical Trials
·
Others
By End User:
- Regulatory Authorities
- Pharmaceutical & Biotechnology Companies
- Academic Research Institutions
- Contract Research Organization
- Other End Users
By
Region:
- North America
o
U.S
o
Canada
o
Mexico
- Europe
o
Germany
o
France
o
UK
o
Italy
o
Spain
o
Rest of Europe
- Asia-Pacific
o
Japan
o
China
o
Australia
o
India
o
South Korea
o
Rest of Asia-Pacific
- Rest of the World
o
Brazil
o
Saudi Arabia
o
Turkey
o
United Arab Emirates
o
Others
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About Crystal Market Research
Crystal
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decisions. It provides both syndicated as well as customized research studies
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