Drug discovery is the process by which a new drug candidate or lead
compound is identified and validated for treating specific disease. Drug
discovery is long term complex process implying large number of steps right
from selecting active ingredient to clinical trials and getting appropriate
approvals. The first stage in drug discovery is to understand disease mechanism
from cellular as well genetic level, in order to identify potential drug
targets. Once disease mechanism is validated, the next step is development of
cell assays to measure activity of similar compounds that can affect activity
of target disease cell. Many biotech and pharmaceutical companies have small
molecule compound libraries which can be used for screening of potential
compounds. In-vivo and in-vitro studies or trials are used to understand
potential course of action of compound and to ascertain toxicology or possible
side effects on human body. Drug discovery involves long term interaction between
research institutes, academics, regulatory bodies & industry and marketing
agencies for commercializing drug for public health.
Drug discovery is a multidiscipline approach integrating disciplines
including genomics, bioinformatics, cell biology and structural biology to name
a few. Advancements in genome sequencing have revolutionized drug discovery
press. Genome sequencing is analyzing complete DNA structure of organism to
understand genetic makeup of organism for accessing underlying cause of various
diseases. Genomic technologies such as statistical genetics, gene sequencing
and gene sequencing analysis are used in experimental and clinical trials for
drug discovery. These genome based technologies aid in drug development by
identifying new target sites, providing exclusive information by computer aided
design of lead compounds and target validation through disease and predictive
toxicology models.
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Increasing elderly population with high risk of developing chronic
diseases, expiry of leading patents and advancements in the field of
biotechnology and molecular biology will drive growth of the global drug
discovery technologies market. In addition, increasing resistance of pathogens
to traditional drugs will increase demand for advanced therapeutics leading to
rapid growth of the market. However, presence of strict approval guidelines,
high cost and long duration of drug discovery process will slow down growth of
the global market.
Major players operating in the global market include Bayer Healthcare AG,
Albany Molecular Research Inc., AstraZeneca plc, Luminex Corporation, Agilent
Technologies, Bio-Rad Laboratories, Albany Molecular Research, Thermo Fisher
Scientific and Charles River Laboratories International, Inc. Strategic
collaborations and partnership are key strategies adopted by market players for
expanding their geographical business boundaries and product portfolio. For
instance, in February 2017, Albany Molecular Research Inc. has formed strategic
alliance with Bruker Daltonics and HighRes Biosolutions to expand their product
portfolio by developing new applications for drug discovery through high mass
spectrometry. This strategic alliance will accelerate growth of Albany
Molecular Research Inc. thereby strengthening global position of the company.
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The continuous advancements in technologies such as 3D printing, next
generation sequencing, gene therapy, stem cell therapies, and microbiomics will
provide ample growth opportunities for market players. Advancements in
Bioinformatics are expected to shape the pharmaceutical industry and will
enhance drug development technologies for giving high value to healthcare
providers as well as patients at low cost. Moreover advancement in technologies
and instrument will further accelerate growth of the market players. For
instance, Thermo Fisher Scientific in June 2016, had launched
ultra-high-performance liquid chromatography (UHPLC) system provides high
speed, reliable and sensitive biocompatible analysis for easy identification of
pharmaceutical ingredients for drug development and designing.
Reasons to Buy This Report
·
Global Advanced
Drug Discovery Technologies Market size & forecast by product &
application.
·
Growth drivers,
pitfalls & industry challenges.
·
Key Advanced Drug
Discovery Technologies Market growth opportunities & emerging business
models.
·
Competitive
benchmarking with market share analysis and company profiles.
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